1、适用范围不同。which指代主句宾语：s+verb+o，which指代o。which指代主句主语：s+verb，which。that的适用范围：不定代词为先行词。any、all、each、every、little、few、no、much、many为先行词。人+物为先行词。
2、用法不相同。which的用法是介词加which等于连词。that用法是序数词为先行词、最高级为先行词。
区别：
1、that和which在从句里都可以做宾语和主语，做宾语时可以省略。
2、在定语从句中,有种说法叫"关宾省",意思是关系代词在限制性定语从句中作宾语可以省略,不管是that，which，还是whom。
3、which能引导非限制性定语从句，that则不行。
4、that与which两者都可指物，常可互换。其区别主要在于：
（1）引导非限制性定语从句时，通常要用which。
如：She received an invitation from her boss, which came as a surprise. 她收到了老板的邀请，这是她意想不到的。
（2）直接放在介词后作宾语时，通常要用which。
如：The tool with which he is working is called a hammer. 他干活用的那个工具叫做锤子。
（3）much, little, none, all, few, every(thing), any(thing), no(thing) 等时，通常用that。
如：There was little that the enemy could do but surrender. 敌人无法,只有投降了。
（4）当先行词有the very, the only, the same 等修饰时，通常用that。
如：This is the only example that I know. 我知道的例子只有这一个。Those are the very words that he used. 那是他的原话。
（5）当先行词有形容词最高级或序数词(包括last, next等)等修饰时，通常用that。
如：This is the best dictionary that I’ve ever used. 这是我用过的最好的词典。
（6）当关系代词在定语从句中用作表语时，通常用that。
如：China is not the country (that) it was. 中国已不是过去的中国了。
（7）当先行词是一个既指人又指物的并列词组时，通常用that。
如：They talked about the persons and things that most impressed them. 他们谈论了使他们印象最深的人和事。
扩展资料
只能用that的几种情况：
1、当先行词为all, much, little, none及由any, every, some, no所构成的复合不定代词时。
如：We should do all that is useful to the people. 我们应该做一切有益于人民的事情。
2、当先行词被any, few, little, no, all, much, some等词修饰时。
如：You can take any seat that is free. 任何空着的座位你都可以坐。
3、当先行词为序数词或被序数词所修饰时。
如：When people talk about the cities of China, the first that comes to my mind is Beijing. 人们谈论起中国的城市的时候，我首先 想到的是北京。
4、当先行词为形容词最高级或被形容词最高级修饰时。
如：The best that I could do was to apologize. 我唯一能做的就是赔礼道歉了。
5、当先行词被the very, the only, the last, the just, the same等修饰时。
如： This is the very book that I'm looking for. 这正是我在找的书。
6、当先行词既包含人又包含物时。
如： They are talking of the heroines and their deeds that interest them. 他们正在谈论他们感兴趣的女英雄及她们的事迹。
7、当先行词是疑问代词who，which，what或主句以这些词开头时。
如：Who that has ever worked together with him doesn't admire him? 曾经和他一起工作过的谁不钦佩他？
8、当先行词为主句表语或关系代词为从句表语时。
如：That's a good book that will help you a lot. 那是本对你很有帮助的书。
9、先行词为time时，当time表示次数，引导词用that, 可省略。 当表示时间，可用that或when引导，都可省略。
如：I do remember the first time(that) I had ever heard the sweetest voice in the world.我很清楚地记得当我第一次听到世界上最美的声音的时候。
只能使用which的情况：
1、在“介词＋关系代词”结构中，关系代词必须用which。
如： The house in which we live is very large. 我们住的房子非常大。
2、先行词为“those＋表事物的复数名词”时， 关系代词通常只用which而不用that。
如：you should grasp well those skills which may be used in the future work。
本回答被网友采纳区别一：意思不同
1、that：那，那个；那；(特指)那，那种，那些；用于某些动词、形容词和名词后，引出从句；(表示结果)如此…以至；(表示希望或愿望)多么。
2、which：哪一个；哪一些；(明确所指的事物)…的那个，…的那些；(进一步提供有关某事物的信息)那个，那些。
区别二：用法不同
1、that可以引导名词性从句，状语从句和强调句，定语从句。
2、which一般只用于定语从句。
区别三：侧重点不同
1、that 用作关系代词，引导限制性定语从句。先行词可人可物，用法相当于who或which。（但是在下列情况下多用that：先行词既有人又有物时；先行词有形容词最高级、序数词、不定代词、very，only等修饰时；先行词是不定代词时）
2、which可引导非限制性定语从句，可直接放在介词后作宾语。which在问句中作为疑问代词，在名词从句中作为连接代词用。which 在从句中作主语时，不能省略。作宾语时在口语中和非正式问题中经常省略。
本回答被网友采纳1.定语从句：修饰一个名词或代词的从句称为定语从句，一般紧跟在它所修饰的先行词后面。
2.关系词：引导定语从句的关联词成为关系词
关系词有关系代词和关系副词。关系代词有that, which, who, whom, whose, as 等；
关系副词有where, when, why等。
关系词常有3个作用：1，引导定语从句。2，代替先行词。3，在定语从句中担当一个成分。
二.关系代词引导的定语从句
1.who指人，在从句中做主语
(1) The boys who are playing football are from Class One.
(2) Yesterday I helped an old man who lost his way.
2. whom指人，在定语从句中充当宾语，常可省略。
(1) Mr. Liu is the person (whom) you talked about on the bus.
(2) Mr. Ling is just the boy whom I want to see.
注意：关系代词whom在口语和非正式语体中常用who代替，可省略。
(3) The man who/whom you met just now is my friend.
3. which指物，在定语从句中做主语或者宾语，做宾语时可省略
(1) Football is a game which is liked by most boys.
(2) This is the pen (which) he bought yesterday.
4. that指人时，相当于who 或者whom；指物时，相当于which。在宾语从句中做主语或者宾语，做宾语时可省略。
(5) The number of the people that/who come to visit the city each year rises one million.
(6) Where is the man that/whom I saw this morning?
5. whose通常指人，也可指物，在定语从句中做定语
(1) He has a friend whose father is a doctor.
(2) I once lived in a house whose roof has fallen in.
whose指物时，常用以下结构来代替
(3) The classroom whose door is broken will soon be repaired.
(4) The classroom the door of which is broken will soon be repaired.
(5) Do you like the book whose cover is yellow?
(6) Do you like the book the color of which is yellow?
三.介词+关系代词引导的定语从句
关系代词在定语从句中做介词宾语时，从句常由介词+关系代词引导
(1) The school (that/which) he once studied in is very famous.
(2) The school in which he once studied is very famous.
(3) Tomorrow I will bring here a magazine (that/which) you asked for.
(4) Tomorrow I will bring here a magazine for which you asked.
(5) We'll go to hear the famous singer (whom/that/who) we have often talked about.
(6) We'll go to hear the famous singer about whom we have often talked.
注意：1. 含有介词的动词短语一般不拆开使用，如：look for, look after, take care of等
(1) This is the watch which/that I am looking for. (T)
(2) This is the watch for which I am looking. (F)
2. 若介词放在关系代词前，关系代词指人时用whom，不可用who或者that；指物时用which，不能用that；关系代词是所有格时用whose
(1) The man with whom you talked is my friend. (T)
(2) The man who/that you talked with is my friend. (F)
(3) The plane in which we flew to Canada is very comfortable. (T)
(4) The plane in that we flew in to Canada is very comfortable. (F)
3.“介词+关系代词”前可有some, any, none, both, all, neither, most, each, few等代词或者数词
(1) He loved his parents deeply, both of whom are very kind to him.
(2) In the basket there are quite many apples, some of which have gone bad.
(3) There are forty students in our class in all, most of whom are from big cities.
四．关系副词引导的定语从句
1. when指时间，在定语从句中做时间状语
(1) I still remember the day when I first came to the school.
(2) The time when we got together finally came.
2. where指地点，在定语从句中做地点状语
(1) Shanghai is the city where I was born.
(2) The house where I lived ten years ago has been pulled down.
3. why指原因，在定语从句中做原因状语
(1) Please tell me the reason why you missed the plane.
(2) I don't know the reason why he looks unhappy today.
注意：关系副词引导的从句可以由“介词+关系代词”引导的从句替换
(1) The reason why/ for which he refused the invitation is not clear,
(2) From the year when/in which he was going to school he began to know what he wanted when he grew up.
(3) Great changes have taken place in the city in which/where I was born.
五．限制性定语从句和非限制性定语从句
限制性定语从句举例：
(1) The teacher told me that Tom was the only person that I could depend on.
(2) China is a country which has a long history.
非限制性定语从句举例：
(1) His mother, who loves him very much, is strict with him.
(2) China, which was founded in 1949, is becoming more and more powerful.
要注意区分以下几个句子的不同
(1) His brother who is now a doctor always encourages him to go to college.
他那当医生的哥哥常鼓励他要考上大学。（他还有其他的哥哥）
(2) His brother, who is now a doctor, always encourages him to go to college.
他的哥哥是当医生的，常鼓励他要考上大学。（他只有一个哥哥）
难点分析
（一）限制性定语从句只能用that 的几种情况
1．当先行词是anything, everything, nothing (something 除外), few, all, none, little, some 等代词时，或者是由every, any, all, some, no, little, few, much 等修饰时
(1) Have you taken down everything that Mr. Li has said?
(2) There seems to be nothing that seems impossible for him in the world.
(3) All that can be done has been done.
(4) There is little that I can do for you.
注意：当先行词指人时，偶尔也可以用who
(4) Any man that/.who has a sense of duty won't do such a thing.
2. 当先行词被序数词修饰
(1) The first place that they visited in London was the Big Ben.
3. 当先行词被形容词最高级修饰时
(1) This is the best film that I have seen.
4. 当形容词被the very, the only修饰时
(1) This is the very dictionary that I want to buy,
(2) After the fire in his house, the old car is the only thing that he owned.
当先行词指人时，偶尔也可以用who
(3) Wang Hua is the only person in our school who will attend the meeting/
5. 当先行词前面有who, which等疑问代词时
(1) Who is the man that is standing there?
(2) Which is the T-shirt that fits me most?
6. 当先行词既有人，也有动物或者物体时
(1) Can you remember the scientist and his theory that we have learned?
（二）关系代词as和which 引导的定语从句
as和which引导非限制性定语从句，有相同之处也有不同之处。具体情况是：
1．As和which都可以在定语从句中做主语或者宾语，代表前面整个句子。
(1) He married her, as/which was natural.
(2) He was honest, as/which we can see.
2. as引导非限制性定语从句，可放在主句之前，或者主句之后，甚至可以切割一个主句；which引导的非限制性定语从句只能放在主句之后。另外，as有“正如……，正像……”的意思
(1) As is known to all, China is a developing country.
(2) He is from the south, as we can see from his accent.
(3) John, as you know, is a famous writer.
(4) He has been to Paris more than several times, which I don't believe.
注意：当主句和从句存在逻辑上的因果关系时，常用which
(5) Tom was always late for school, which made his teacher angry.
3. 当先行次受such, the same修饰时，常用as
(1) I have never heard such a story as he tells.
(2) He is not such a fool as he looks.
(3) This is the same book as I lost last week.
注意：当先行次由the same修饰时，偶尔也用that引导定语从句，但是和由as 所引导的定语从句意思不同
(4) She wore the same dress that she wore at Mary's wedding.
她穿着她在Mary婚礼上穿过的一条裙子。
(5) She wore the same dress as her young sister wore.
她穿着和她妹妹所穿的一样的裙子。
（三）以the way为先行词的定语从句通常由in which, that引导，而且通常可以省略。
(1) The way in which/ that/./ he answered the question was surprising.
(四) but 有时也可以做关系词引导定语从句
(1) There are very few but understand his idea. ( but= who don't )
(五)区分定语从句和同位语从句
1．定语从句修饰先行词，它和先行词是修饰关系；同位语从句说明先行词的具体内容，是补充说明的关系
(1) The plane that has just taken off is for London. 定语从句
(2) The fact that he has been dead is clear. 同位于从句
2．定语从句由关系代词或者关系副词引导，关系词在句中充当成分，有时可以省略；同位语从句主要由that引导，在句中一般不做成分；句子也可以由when, where, how, why, whether, what等词引导，充当成分
(1) The news he told me is true.
(2) The news that he has just died is true.
(3) The problem that we are facing now is how we can collect so much money. 定语
(4) The problem how we can collect so much money is difficult to solve.
3. 同位语从句和先行词一般可以用be动词发展成一个完整的句子，而定语从句不可以
(1) The idea that we could ask the teacher for advice is wonderful.
(2) The idea was that we could ask the teacher for advice.
(3) The fact that the earth moves around the earth is known to all. 同位语
(4) The fact is that the earth moves around the earth.
参考资料：http://www.jxue.com/mid
2。that(指物,人)=which（指物）+who（指人）
3.在there be 句型中，只用that，不用which
4.在不定代词，如：anything, nothing, the one, all, much, few, any, little等作先行词时，只用that，不用which
5.先行词有the only, the very,the same,the last,just修饰时，只用that
6.先行词为序数词、数词、形容词最高级时，只用that
7.先行词既有人，又有物时
书上没有吗？
我记得人教版必修2后面有啊本回答被提问者采纳