1、意思不同
respond to是一个固定的搭配、词组。意思是回应，响应等。
例句：
The best way to respond to a flame is to ignore it.
回应谩骂性电子邮件的最好办法就是置之不理。
而respond on不是词组，只是碰巧在一起，意思是在......上作出反应。这里的on取决于后面的单词或指代事物等内容，和后面的内容有关，与respond无关。
例句：
The company said Wednesday it plans to
respond on the matter sometime early next year.
苹果公司上周三表示，计划在明年年初就此事作出回应。
2、读音不同
respond to读音：英 [rɪˈspɒnd tu] 美 [rɪˈspɑːnd tu]
respond on读音：英 [rɪˈspɒnd ɒn] 美 [rɪˈspɑːnd ɑːn]
扩展资料：
意思与之相似的还有：reply to和respond with
1、reply to
读音：英 [rɪˈplaɪ tu] 美 [rɪˈplaɪ tu]
v.答复；回答
例句：
The world community has been slow to respond to the crisis
国际社会对这次危机反应迟缓。
2、respond with
读音：英 [rɪˈspɒnd wɪð] 美 [rɪˈspɑːnd wɪð]
回复
例句：
Please respond with prices and technical specifications.
请响应价格和技术规格。
respond to和respond on 的区别在于： respond to： 响应； 回答； 对……反应。是固定词组。respond on：在......反应。不是固定词组。
respond to的意思是对......反应。 respond on的意思是：在......反应。 读音[rɪ'spɒnd tu] 和[rɪ'spɒnd an]。
例如：
Must be able to work independently, respond to tight deadlines and be highly productive.
必须能够独立工作，有极强的时间观念，工作效率高。
An event handler, onSelect, is added to every list element to respond on a click.
事件处理函数，onSelect，添加到每个列表元素以在点击时响应。
respond to的近义词有：
answer
回答
reply
回答
retort
反驳
react
反应
return
返回
respond on的近义词有：
answer back
顶嘴
rejoin
（使）再结合...
take action
采取行动
counter
柜台
act
行为
act on
词意辩解：espond by, respond with
1.前者指以做某事的方式报答某人; 后者指以某东西报答某人。
2.respond by后多接动名词,而respond with后多接名词。
还有以下短文：
I will persist until I succeed. In the Orient young bulls aretested for the fight arena in a certain
manner. Each is brought to the
ring and allowed to respondattack a onpicador who pricks them
bravery of each bull ，We Are Responsible for Our Life. And nobody else.
requires the assistance and cooperation of others, our success can never
be left to anyone else. Luck is not a strategy.He will respond to that, not me. In my heart, the
good life in since I sensible to toseveral years。
several years, deeply feel the progress and prosperity, it also makes my future life is more,
more beautiful vision of love.
I